产品货号:
Z23506
中文名称:
PIWIL2抗体
英文名称:
Anti-PIWIL2 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
| 抗体名称 | Anti-PIWIL2 Antibody |
| 指标别名 | Cancer/testis antigen 80;CT80;HILI;mili;piwi like 2 (Drosophila);Piwi like protein 2;PIWIL1L;PIWIL2 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | ELISA,IHC |
| 基因名称 | PIWIL2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | PIWI-L2 antibody was raised against a 14 amino acid synthetic peptide near the center of human PIWI-L2.The immunogen is located within amino acids 460 - 510 of PIWI-L2. |
| 计算分子量 | 110kDa |
| 成分 | PIWI-L2 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | PIWI-L2 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
| 背景资料 | PIWI-L2 is a member of the PIWI subfamily of Argonaute proteins,evolutionarily conserved proteins containing both PAZ and Piwi motifs that are crucial for the biogenesis and function of small non-coding RNAs and play important roles in stem cell self-renewal,RNA silencing,and translational regulation in diverse organisms.PIWI-L2 has been implicated in multiple roles including stem cell self-renewal and is highly expressed in many breast cancers.In these tumors,PIWI-L2 silences the expression of STAT3,a regulator of Bcl-XL and cyclin D1,allowing the proliferation and survival of breast cancer stem cells.Recent studies have shown that overexpression of PIWI-like proteins are potential biomarkers for colon and other cancers. |
| Uniprot ID | Q8TC59 |
| 基因名全称 | Piwi-like 2 |
| 蛋白名全称 | Piwi-like 2 |
| 推荐稀释比 | PIWI-L2 antibody can be used for detection of PIWI-L2 by immunohistochemistry at 5μg/mL.Antibody validated:Immunohistochemistry in human samples.All other applications and species not yet tested. |
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